Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201736 | 0.83 | DCPS (0.38) | HTR2AHTR2CHTR2BRIPK1DCPS | |
| SCHEMBL20201732 | 0.77 | DCPS (0.38) | HTR2AHTR2CHTR2BRIPK1DCPS | |
| SCHEMBL765009 | 0.73 | GRM2 (0.43) | HTR2AHTR2CHTR2BRIPK1DCPS | |
| SCHEMBL20204815 | 0.73 | HTR1A (0.47) | RIPK1 | |
| SCHEMBL18373998 | 0.72 | CNR2 (0.39) | HTR2AHTR2CHTR2BRIPK1DCPS | |
| SCHEMBL20201734 | 0.70 | KMO (0.39) | HTR2CHTR2BRIPK1DCPSSCN9A | |
| SCHEMBL11962822 | 0.70 | HTR2A (0.43) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL16662423 | 0.69 | TSHR (0.47) | HTR2BRIPK1 | |
| SCHEMBL26770363 | 0.69 | HTR2C (0.47) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL20201699 | 0.68 | PDE10A (0.40) | HTR2AHTR2CHTR2BRIPK1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |