Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745570 | 0.83 | MAPT (0.49) | KMOHTR2CHTR2BGRM2 | |
| SCHEMBL20204815 | 0.82 | HTR1A (0.47) | RIPK1 | |
| SCHEMBL21325097 | 0.81 | CNR2 (0.39) | CNR2 | |
| SCHEMBL21325226 | 0.81 | RIPK1 (0.40) | RIPK1CNR2HTR2CHTR2B | |
| SCHEMBL20201732 | 0.79 | DCPS (0.38) | DCPSRIPK1SCN9AHTR2CHTR2B | |
| SCHEMBL18122083 | 0.79 | MAPT (0.53) | KMORIPK1CNR2 | |
| SCHEMBL20201737 | 0.77 | CNR2 (0.40) | KMOCNR2SCN9A | |
| SCHEMBL1814155 | 0.76 | KMO (0.43) | KMOCNR2SCN9A | |
| SCHEMBL4445968 | 0.74 | KMO (0.39) | KMOCNR2SCN9A | |
| SCHEMBL1814275 | 0.74 | LMNA (0.40) | KMOCNR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098206-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |