Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201732 | 0.82 | DCPS (0.38) | RIPK1 | |
| SCHEMBL20201734 | 0.82 | KMO (0.39) | RIPK1 | |
| SCHEMBL14943724 | 0.79 | HTR1A (0.42) | HTR1AALDH1A1KDM4EMAPTRIPK1 | |
| SCHEMBL16662423 | 0.78 | TSHR (0.47) | POLBL3MBTL1HPGDALDH1A1KDM4E | |
| SCHEMBL14315390 | 0.77 | HPGD (0.62) | HTR1APOLBL3MBTL1HPGDALDH1A1 | |
| SCHEMBL816186 | 0.76 | RIPK1 (0.36) | HPGDRIPK1 | |
| SCHEMBL20201736 | 0.75 | DCPS (0.38) | RIPK1 | |
| SCHEMBL10753281 | 0.74 | ALDH1A1 (0.47) | HTR1APOLBL3MBTL1HPGDALDH1A1 | |
| SCHEMBL14877969 | 0.73 | KMT2A (0.43) | HTR1AHPGDALDH1A1KDM4EMAPT | |
| SCHEMBL20201737 | 0.73 | CNR2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098209-A1 | AMINO SULFONYL COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |