Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 9/20 | 0.39 |
| ▸ | IL1B | P01584 | 2/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275500 | 0.82 | CASP3 (0.45) | CASP3CASP1 | |
| SCHEMBL12809931 | 0.82 | CASP3 (0.45) | CASP3CASP1 | |
| SCHEMBL13891807 | 0.80 | CASP3 (0.41) | CASP3ITGB3ITGA2BCASP1IL1B | |
| SCHEMBL18132943 | 0.80 | CASP3 (0.41) | CASP3ITGB3ITGA2BCASP1IL1B | |
| SCHEMBL18541614 | 0.79 | CASP3 (0.46) | FOLH1CASP3CASP1 | |
| SCHEMBL8201263 | 0.79 | CTSK (0.44) | KDM4EKDM5CPHF8KDM2AEGLN1 | |
| SCHEMBL22271706 | 0.77 | CASP3 (0.39) | CASP3CASP1IL1B | |
| SCHEMBL7431065 | 0.77 | CASP1 (0.63) | CASP1IL1B | |
| SCHEMBL3520937 | 0.76 | CA2 (0.59) | FOLH1CASP3CASP1 | |
| SCHEMBL8360127 | 0.75 | CASP3 (0.43) | KDM4ECASP3CASP1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147286-A1 | BONE FRACTURE REPAIR BY TARGETING OF AGENTS THAT PROMOTE BONE HEALING | UNIVERSITY OF UTAH | 2018-05-31 | — | — | US | disclosed |
| US-20180147286-A1 | BONE FRACTURE REPAIR BY TARGETING OF AGENTS THAT PROMOTE BONE HEALING | UNIVERSITY OF UTAH | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147286-A1 | BONE FRACTURE REPAIR BY TARGETING OF AGENTS THAT PROMOTE BONE HEALING | CTSK, CTSG, MMP13 | KDM4E 2733/4885KDM5C 3334/4885PHF8 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.