SCHEMBL20208940

SCHEMBL20208940

C/C(=N\[C@H]1CCCC[C@H]1C(C)C)c1cccc(/C(C)=N/[C@@H]2CCCC[C@@H]2C(C)C)n1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
DUSP3 P51452 1/20 0.32
PTPN11 Q06124 1/20 0.32
ALDH1A1 P00352 2/20 0.31
ALOX15 P16050 1/20 0.31
HKDC1 Q2TB90 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15906875 0.75 MEN1 (0.31) KMT2AALDH1A1
SCHEMBL4887030 0.74 ALDH1A1 (0.54) KMT2ADUSP3PTPN11ALDH1A1ALOX15
SCHEMBL4887039 0.74 ALDH1A1 (0.54) KMT2ADUSP3PTPN11ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL6119092 0.72 ALDH1A1 (0.51) KMT2ADUSP3PTPN11ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL7180535 0.72 ALDH1A1 (0.51) KMT2ADUSP3PTPN11ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL7175502 0.72 ALDH1A1 (0.51) KMT2ADUSP3PTPN11ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL7175999 0.72 ALDH1A1 (0.51) KMT2ADUSP3PTPN11ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL7173330 0.72 ALDH1A1 (0.51) KMT2ADUSP3PTPN11ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL7183213 0.72 ALDH1A1 (0.51) KMT2ADUSP3PTPN11ALDH1A1ALOX15
SCHEMBL15840503 0.68 ALDH1A1 (0.41) KMT2AALDH1A1ALOX15NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10441946-B2 Linear alpha-olefin catalysts and preparation and use thereof APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) 2019-10-15 US disclosed
US-20180147571-A1 NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180147571-A1 NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF UBE2L3, RNF168, AGL KMT2A 3932/4885DUSP3 4835/4885PTPN11 4780/4885
US-10441946-B2 Linear alpha-olefin catalysts and preparation and use thereof UBE2L3, COG8, ACSL3 KMT2A 3907/4885DUSP3 4808/4885PTPN11 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.