SCHEMBL20211740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30800214	1.00	KEAP1 (0.39)	KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD
	SCHEMBL20211769	0.90	TSHR (0.36)	SMN1; SMN2ALDH1A1KDM4EHPGDADORA2B
	SCHEMBL19810232	0.90	ALDH1A1 (0.38)	SMN1; SMN2ALDH1A1KDM4EADORA2BHSD17B10
	SCHEMBL30110483	0.90	ALDH1A1 (0.38)	SMN1; SMN2ALDH1A1KDM4EADORA2BHSD17B10
	SCHEMBL2670126	0.89	ALDH1A1 (0.39)	ALDH1A1KDM4EHPGDADORA2BHSD17B10
	SCHEMBL20211734	0.89	MAOA (0.39)	SMN1; SMN2ALDH1A1KDM4EHPGDNPC1
	SCHEMBL25760270	0.88	ADORA2B (0.38)	SMN1; SMN2ALDH1A1KDM4EHPGDNPC1
	SCHEMBL27213496	0.88	ALDH1A1 (0.41)	SMN1; SMN2ALDH1A1KDM4EHPGDADORA2B
	SCHEMBL19810311	0.88	ADORA2A (0.35)	SMN1; SMN2ALDH1A1ADORA2BHSD17B10TSHR
	SCHEMBL19810310	0.87	ADORA2B (0.38)	ALDH1A1KDM4EHPGDADORA2BHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.