Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | POR | P16435 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827603 | 0.73 | — | — | |
| SCHEMBL6224785 | 0.67 | KDM4E (0.39) | KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL8580205 | 0.65 | THRB (0.40) | KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL9643236 | 0.64 | — | — | |
| SCHEMBL5609721 | 0.62 | — | — | |
| SCHEMBL4324761 | 0.62 | ALDH1A1 (0.38) | KDM4ELMNAALDH1A1 | |
| SCHEMBL115390 | 0.61 | — | — | |
| SCHEMBL4880738 | 0.60 | MMP1 (0.41) | KDM4ELMNAALDH1A1MAPTTHRB | |
| SCHEMBL3281430 | 0.60 | TSHR (0.43) | KDM4EALDH1A1 | |
| SCHEMBL20239676 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899878-B2 | Phosphorus-containing caprolactone monomers for synthesis of flame retardant polycaprolactones | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-01-26 | — | — | US | disclosed |
| US-10883050-B2 | Cross-linkable flame retardant materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2021-01-05 | — | — | US | disclosed |
| US-10640608-B2 | Phosphorus-containing caprolactone monomers for synthesis of flame retardant polycaprolactones | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190248955-A1 | PHOSPHORUS-CONTAINING CAPROLACTONE MONOMERS FOR SYNTHESIS OF FLAME RETARDANT POLYCAPROLACTONES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-08-15 | — | — | US | disclosed |
| US-10336861-B2 | Phosphorus-containing caprolactone monomers for synthesis of flame retardant polycaprolactones | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180362852-A1 | CROSS-LINKABLE FLAME RETARDANT MATERIALS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-12-20 | — | — | US | disclosed |
| US-10155907-B2 | Cross-linkable flame retardant materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-12-18 | — | — | US | disclosed |
| US-10106564-B2 | Furan-containing flame retardant molecules | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-10-23 | — | — | US | disclosed |
| US-20180298044-A1 | FURAN-CONTAINING FLAME RETARDANT MOLECULES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-10-18 | — | — | US | disclosed |
| US-20180291143-A1 | PHOSPHORUS-CONTAINING CAPROLACTONE MONOMERS FOR SYNTHESIS OF FLAME RETARDANT POLYCAPROLACTONES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-10-11 | — | — | US | disclosed |
| US-20180163139-A1 | CROSS-LINKABLE FLAME RETARDANT MATERIALS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-06-14 | — | — | US | disclosed |
| US-20180162888-A1 | FURAN-CONTAINING FLAME RETARDANT MOLECULES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10106564-B2 | Furan-containing flame retardant molecules | PFAS, PFKFB2, PFKFB4 | KDM4E 1993/4885MAPK1 905/4885LMNA 2482/4885 |
| US-20180162888-A1 | FURAN-CONTAINING FLAME RETARDANT MOLECULES | PFAS, PFKFB2, PFKFB4 | KDM4E 1993/4885MAPK1 905/4885LMNA 2482/4885 |
| US-20180298044-A1 | FURAN-CONTAINING FLAME RETARDANT MOLECULES | PFAS, PFKFB2, PFKFB4 | KDM4E 1993/4885MAPK1 905/4885LMNA 2482/4885 |
| US-10155907-B2 | Cross-linkable flame retardant materials | PFAS, PFKFB2, PFKFB4 | KDM4E 1390/4885MAPK1 1130/4885LMNA 1295/4885 |
| US-20180362852-A1 | CROSS-LINKABLE FLAME RETARDANT MATERIALS | PFAS, PFKFB2, PFKFB4 | KDM4E 1390/4885MAPK1 1130/4885LMNA 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.