Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Calcium Chloride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Calcium Chloride SCHEMBL27770926 | 1.00 | — | — | |
| Calcium Chloride SCHEMBL27344866 | 1.00 | — | — | |
| Calcium Chloride SCHEMBL28855954 | 1.00 | TSHR (0.30) | TSHRLMNACYP2A6ALDH1A1ALOX15 | |
| Calcium Chloride SCHEMBL27480595 | 1.00 | TSHR (0.30) | TSHRLMNACYP2A6ALDH1A1ALOX15 | |
| Calcium Chloride SCHEMBL29392100 | 1.00 | — | — | |
| Calcium Chloride SCHEMBL29249624 | 1.00 | TSHR (0.30) | TSHRLMNACYP2A6ALDH1A1ALOX15 | |
| Calcium Chloride SCHEMBL28681482 | 1.00 | TSHR (0.30) | TSHRLMNACYP2A6ALDH1A1ALOX15 | |
| Calcium Chloride SCHEMBL28983949 | 1.00 | TSHR (0.30) | TSHRLMNACYP2A6ALDH1A1ALOX15 | |
| Calcium Chloride SCHEMBL22532692 | 1.00 | — | — | |
| Calcium Chloride SCHEMBL28063381 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138709-A | Preparation method of polyurethane sponge | 广东万康新材料科技有限公司 | 2020-05-12 | — | — | CN | claimed |
| EP-3551201-A1 | METHODS AND COMPOSITIONS RELATING TO ISOLATED AND PURIFIED MICROBES | Pendulum Therapeutics, Inc. (US) | 2019-10-16 | — | — | EP | claimed |
| WO-2018106844-A1 | METHODS AND COMPOSITIONS RELATING TO ISOLATED AND PURIFIED MICROBES | WHOLE BIOME INC. (US) | 2018-06-14 | — | — | WO | claimed |
| CN-111138709-B | Preparation method of polyurethane sponge | 广东万康新材料科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-115924932-A | Preparation method of calcium hexaborate | 中国科学院青海盐湖研究所 | 2023-04-07 | — | — | CN | disclosed |
| EP-3777836-A1 | OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES | ALLERGAN, INC. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-111138709-A | Preparation method of polyurethane sponge | 广东万康新材料科技有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-20200121738-A1 | METHODS AND COMPOSITIONS RELATING TO ISOLATED AND PURIFIED MICROBES | Pendulum Therapeutics, Inc. | 2020-04-23 | — | — | US | disclosed |
| EP-3551201-A1 | METHODS AND COMPOSITIONS RELATING TO ISOLATED AND PURIFIED MICROBES | Pendulum Therapeutics, Inc. (US) | 2019-10-16 | — | — | EP | disclosed |
| WO-2018106844-A1 | METHODS AND COMPOSITIONS RELATING TO ISOLATED AND PURIFIED MICROBES | WHOLE BIOME INC. (US) | 2018-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200121738-A1 | METHODS AND COMPOSITIONS RELATING TO ISOLATED AND PURIFIED MICROBES | SI, CYP2C19, FABP2 | TSHR 4320/4885LMNA 4264/4885CYP2A6 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.