SCHEMBL20249062

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18321922	0.95	GABRA2 (0.46)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL1550851	0.90	GABRA2 (0.43)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL1551144	0.88	RAB9A (0.45)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL20249059	0.81	NPC1 (0.41)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL20249060	0.79	DDR1 (0.41)	NPC1RAB9AMAPT
	SCHEMBL549152	0.77	GABRA2 (0.58)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL548181	0.76	POLB (0.59)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL18327913	0.76	NPC1 (0.43)	GABRA2GABRB2NPC1RAB9AGABRB3
	SCHEMBL1550424	0.75	RAB9A (0.53)	NPC1RAB9AMAPTGRM1
	SCHEMBL18327912	0.74	NR1I2 (0.41)	NPC1RAB9AGRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.