Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327913 | 0.95 | NPC1 (0.43) | NPC1RAB9ALMNANFKB1GRM1 | |
| SCHEMBL20249062 | 0.81 | GABRA2 (0.44) | NPC1RAB9AMAPTNPBWR1GRM1 | |
| SCHEMBL20249060 | 0.80 | DDR1 (0.41) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL29624443 | 0.79 | NPC1 (0.43) | NPC1RAB9ALMNAGRM1GABRB3 | |
| SCHEMBL20249061 | 0.79 | PTGS2 (0.42) | NPC1RAB9ALMNANFKB1NFKB2 | |
| SCHEMBL20526158 | 0.79 | NPC1 (0.43) | NPC1RAB9ALMNAGRM1GABRB3 | |
| SCHEMBL18321922 | 0.76 | GABRA2 (0.46) | NPC1RAB9AGRM1GABRB3GABRA2 | |
| SCHEMBL18327912 | 0.75 | NR1I2 (0.41) | NPC1RAB9ALMNAGRM1DDR1 | |
| SCHEMBL19017319 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL29755704 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2MAPTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548316-B2 | Diarylazole compound and harmful organism control agent | NIPPON SODA CO., LTD. (JP) | 2020-02-04 | — | — | US | disclosed |
| US-20180160686-A1 | DIARYLAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180160686-A1 | DIARYLAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10548316-B2 | Diarylazole compound and harmful organism control agent | L3MBTL1, L3MBTL3, L3MBTL4 | NPC1 2264/4885RAB9A 1424/4885LMNA 2558/4885 |
| US-20180160686-A1 | DIARYLAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | L3MBTL1, L3MBTL3, L3MBTL4 | NPC1 2264/4885RAB9A 1424/4885LMNA 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.