Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985872 | 0.77 | ELANE (0.51) | ELANEKDM4EALDH1A1JAK2IGF1R | |
| SCHEMBL17413769 | 0.75 | ALDH1A1 (0.41) | ELANEKDM4EALDH1A1JAK2IGF1R | |
| SCHEMBL20256150 | 0.73 | MAPT (0.50) | ELANEKDM4EALDH1A1PIM1CSNK2A2 | |
| SCHEMBL20256167 | 0.70 | GPR3 (0.44) | GPR3KDM4EALDH1A1PIM1CSNK2A2 | |
| SCHEMBL19044522 | 0.69 | KDM4E (0.47) | ELANEKDM4EALDH1A1JAK2IGF1R | |
| SCHEMBL19044531 | 0.69 | NPY5R (0.41) | ELANEKDM4EALDH1A1JAK2IGF1R | |
| SCHEMBL8485972 | 0.67 | MAOA (0.46) | GPR3ELANEKDM4EALDH1A1C1R | |
| SCHEMBL19045020 | 0.66 | L3MBTL1 (0.43) | ELANEKDM4EALDH1A1JAK2IGF1R | |
| SCHEMBL18132488 | 0.66 | MEN1 (0.42) | KDM4EALDH1A1SRCCDK2LMNA | |
| SCHEMBL29387122 | 0.65 | GPR3 (1.00) | GPR3KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978491-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | Merck Patent GmbH (DE) | 2022-04-06 | — | — | EP | disclosed |
| US-20200066994-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2020-02-27 | — | — | US | disclosed |
| WO-2018104195-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200066994-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | CYCS, OCIAD2, OCIAD1 | GPR3 1007/4885ELANE 925/4885KDM4E 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.