Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17413769 | 0.86 | ALDH1A1 (0.41) | MAPTMEN1KMT2AAPEX1PABPC1 | |
| SCHEMBL7534095 | 0.80 | MAPT (0.58) | MAPTMEN1KMT2AAPEX1PABPC1 | |
| SCHEMBL7535432 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2AAPEX1PABPC1 | |
| SCHEMBL10985872 | 0.77 | ELANE (0.51) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL19162426 | 0.76 | MAPT (0.50) | MAPTMEN1KMT2AAPEX1PABPC1 | |
| SCHEMBL20256152 | 0.73 | GPR3 (0.44) | MAPTKMT2APABPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL460367 | 0.72 | MAOA (0.56) | MAPTMEN1KMT2AAPEX1PABPC1 | |
| SCHEMBL19044531 | 0.72 | NPY5R (0.41) | MAPTPABPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19044522 | 0.72 | KDM4E (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL25470096 | 0.70 | ALDH1A1 (0.43) | MAPTMEN1KMT2AMAOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978491-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | Merck Patent GmbH (DE) | 2022-04-06 | — | — | EP | disclosed |
| EP-3548477-B1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-20200066994-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2020-02-27 | — | — | US | disclosed |
| WO-2018104195-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200066994-A1 | NITROGEN-CONTAINING HETEROCYCLES FOR USE IN OLEDS | CYCS, OCIAD2, OCIAD1 | MAPT 2949/4885MEN1 3952/4885KMT2A 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.