Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443985 | 0.95 | ALDH1A1 (0.46) | ALDH1A1PRMT3MCL1LMNAHSD17B10 | |
| SCHEMBL22064537 | 0.82 | CA1 (0.38) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL1463416 | 0.82 | CA1 (0.38) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL19509410 | 0.80 | KDM4E (0.39) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL17449669 | 0.80 | MEN1 (0.48) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL31758443 | 0.80 | KDM4E (0.39) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL12443072 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL9971593 | 0.78 | TERT (0.39) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL20801526 | 0.78 | ALDH1A1 (0.35) | ALDH1A1PRMT3MCL1LMNARECQL | |
| SCHEMBL13912379 | 0.78 | ALDH1A1 (0.35) | ALDH1A1PRMT3MCL1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10976306-B2 | Protein degradation inducing tag and usage thereof | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20180164289-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10976306-B2 | Protein degradation inducing tag and usage thereof | SENP8, SENP6, SENP7 | ALDH1A1 4039/4885PRMT3 2179/4885MCL1 1094/4885 |
| US-20180164289-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | SENP8, SENP6, SENP7 | ALDH1A1 4039/4885PRMT3 2179/4885MCL1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.