Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.69 |
| ▸ | TUBB | P07437 | 2/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386469 | 0.89 | TUBB4A (0.67) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL3241112 | 0.88 | TUBB4A (0.69) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL2027525 | 0.87 | LMNA (0.66) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL4513166 | 0.86 | SMN1; SMN2 (0.73) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL25172097 | 0.84 | ALDH1A1 (0.62) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL2028783 | 0.84 | SMN1; SMN2 (0.55) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL2029440 | 0.83 | LMNA (0.53) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL4420449 | 0.83 | LMNA (0.61) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL32676771 | 0.82 | SMN1; SMN2 (0.53) | LMNATSHRALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL20116117 | 0.81 | LMNA (0.72) | LMNATSHRALOX15MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136823-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2011-06-09 | — | — | US | claimed |
| US-20260048047-A1 | SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE | SCRIPPS RESEARCH INST (US) | 2026-02-19 | — | — | US | disclosed |
| WO-2024030121-A1 | SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-02-08 | — | — | WO | disclosed |
| US-8338599-B2 | Compounds having a potentiating effect on the activity of ethionamide and uses thereof | INSTITUT PASTEUR DE LILLE (FR) | 2012-12-25 | — | — | US | disclosed |
| US-20110136823-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136823-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | EPX, PGLS, ENPEP | LMNA 1439/4885TSHR 2305/4885ALOX15 648/4885 |
| US-20260048047-A1 | SMALL-MOLECULE ACTIVATORS OF MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE | FNTB, PDE7A, TBL3 | LMNA 1838/4885TSHR 620/4885ALOX15 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.