SCHEMBL20264382

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29940569	1.00	LMNA (0.45)	LMNACA2CA1MAPK1POLB
	SCHEMBL20277899	0.89	POLB (0.42)	POLBMEN1KMT2AGAACYP1A2
	SCHEMBL29940563	0.75	POLB (0.45)	LMNAPOLBMEN1KMT2AGAA
	SCHEMBL20264395	0.75	POLB (0.45)	LMNAPOLBMEN1KMT2AGAA
	SCHEMBL9001866	0.73	MAPK1 (0.49)	LMNACA2CA1MAPK1POLB
	SCHEMBL21305023	0.70	ALDH1A1 (0.36)	LMNACA2MAPK1CYP3A4ALDH1A1
	SCHEMBL26032149	0.69	POLB (0.48)	POLBMEN1KMT2AGAACYP2C9
	SCHEMBL11184627	0.69	POLB (0.48)	POLBMEN1KMT2AGAACYP2C9
	SCHEMBL20278053	0.69	SMN1; SMN2 (0.45)	LMNAPOLBMEN1KMT2ACYP1A2
	SCHEMBL1882756	0.69	CA2 (0.59)	CA2CA1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.