Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274136 | 0.88 | MEN1 (0.42) | TSHRKMT2ACYP2D6CYP2C19 | |
| SCHEMBL20274170 | 0.85 | L3MBTL1 (0.44) | ALDH1A1KDM4EKMT2ALMNATBXAS1 | |
| SCHEMBL20274139 | 0.77 | HRH4 (0.47) | ALDH1A1TSHRKDM4EPOLBKMT2A | |
| SCHEMBL20274205 | 0.75 | SOS1 (0.51) | KMT2AAKR1C3EPHX2LMNAKCNH2 | |
| SCHEMBL20274216 | 0.75 | HTR2B (0.46) | ALDH1A1TSHRKDM4EPOLBKMT2A | |
| SCHEMBL20274189 | 0.72 | L3MBTL1 (0.44) | ALDH1A1KDM4EPOLBKMT2ATBXAS1 | |
| SCHEMBL20274113 | 0.71 | SIGMAR1 (0.39) | ALDH1A1TSHRKDM4EKMT2AAKR1C3 | |
| SCHEMBL20274204 | 0.70 | EPHX2 (0.40) | ALDH1A1TSHRKDM4EPOLBKMT2A | |
| SCHEMBL20274196 | 0.69 | HRH4 (0.73) | ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL2958198 | 0.66 | MAPT (0.50) | ALDH1A1TSHRKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |