Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 9/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20283427 | 0.99 | IDE (0.40) | IDEOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL22916013 | 0.93 | MMP1 (0.36) | IDEOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL22916085 | 0.92 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20283426 | 0.92 | GHSR (0.39) | IDEMEN1 | |
| SCHEMBL20283646 | 0.92 | IDE (0.34) | IDEOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL20283428 | 0.91 | GHSR (0.34) | IDEOPRM1OPRD1OPRK1 | |
| SCHEMBL22916030 | 0.88 | OPRM1 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL24917456 | 0.86 | CTSS (0.34) | IDE | |
| SCHEMBL22916032 | 0.86 | GHSR (0.35) | IDEMEN1 | |
| SCHEMBL22916029 | 0.86 | GHSR (0.41) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560361-B2 | Simplified structural mimetics of AIPS as quorum sensing inhibitors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-01-24 | — | — | US | disclosed |
| US-20180170889-A1 | Simplified Structural Mimetics of AIPS as Quorum Sensing Inhibitors | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560361-B2 | Simplified structural mimetics of AIPS as quorum sensing inhibitors | AIPL1, AIP, PYM1 | IDE 1870/4885OPRM1 1628/4885OPRD1 2470/4885 |
| US-20180170889-A1 | Simplified Structural Mimetics of AIPS as Quorum Sensing Inhibitors | AIP, AIPL1, CGAS | IDE 1155/4885OPRM1 3375/4885OPRD1 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.