Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997369 | 0.88 | PORCN (0.47) | WNT3APORCN | |
| SCHEMBL19997380 | 0.85 | WNT3A (0.44) | WNT3APORCN | |
| SCHEMBL23416906 | 0.80 | PORCN (0.48) | WNT3APORCN | |
| SCHEMBL19626366 | 0.80 | PORCN (0.42) | WNT3APORCN | |
| SCHEMBL21935695 | 0.79 | PORCN (0.46) | PORCN | |
| SCHEMBL23416909 | 0.78 | PORCN (0.58) | WNT3APORCN | |
| SCHEMBL19997367 | 0.77 | DEGS1 (0.41) | WNT3A | |
| SCHEMBL19626536 | 0.77 | MAPT (0.47) | — | |
| SCHEMBL21413005 | 0.77 | GRM5 (0.37) | PORCNGRM5 | |
| SCHEMBL19626637 | 0.76 | PORCN (0.51) | WNT3APORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170932-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170932-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | WNT1, WNT3A, CTNNB1 | WNT3A 2/4885PORCN 3761/4885GRIN2B 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.