Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21935824 | 0.88 | DEGS1 (0.42) | DEGS1PARP1ALDH1A1TRPA1WNT3A | |
| SCHEMBL17626187 | 0.79 | RAB9A (0.53) | TRPA1CYP1A2LMNA | |
| SCHEMBL21935457 | 0.74 | KMT2A (0.46) | DEGS1PARP1ALDH1A1TRPA1MEN1 | |
| SCHEMBL19997380 | 0.73 | WNT3A (0.44) | TRPA1WNT3A | |
| SCHEMBL17628656 | 0.72 | RAB9A (0.56) | TRPA1KMT2ACYP1A2MAPT | |
| SCHEMBL21935377 | 0.71 | TRPA1 (0.55) | TRPA1CYP1A2TSHRLMNA | |
| SCHEMBL21935664 | 0.70 | TRPA1 (0.52) | TRPA1HSD17B10CYP1A2LMNA | |
| SCHEMBL17626308 | 0.70 | MAPK1 (0.59) | ALDH1A1TRPA1KMT2ACYP1A2TSHR | |
| SCHEMBL17626184 | 0.69 | RAB9A (0.61) | DEGS1TRPA1KMT2ACYP1A2TSHR | |
| SCHEMBL17626299 | 0.69 | PORCN (0.59) | ALDH1A1TRPA1HSD17B10CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230366031-A1 | KIT FOR IDENTIFYING MALIGNANCY, AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-11-16 | — | — | US | disclosed |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-06-08 | — | — | US | disclosed |
| US-11649505-B2 | Kit for identifying malignancy, and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-05-16 | — | — | US | disclosed |
| US-20210155623-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-05-27 | — | — | US | disclosed |
| US-9926320-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649505-B2 | Kit for identifying malignancy, and uses thereof | KIT, WNT1, WNT3 | DEGS1 3677/4885PARP1 3824/4885ALDH1A1 2630/4885 |
| US-20230366031-A1 | KIT FOR IDENTIFYING MALIGNANCY, AND USES THEREOF | KIT, WNT1, WNT3 | DEGS1 3677/4885PARP1 3824/4885ALDH1A1 2630/4885 |
| US-20230174533-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | DEGS1 1916/4885PARP1 392/4885ALDH1A1 1754/4885 |
| US-20210155623-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | WNT1, WNT3A, WNT3 | DEGS1 1916/4885PARP1 392/4885ALDH1A1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.