Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348874 | 0.82 | PRKCA (0.38) | PRKCAPOLBGAANPSR1TKT | |
| SCHEMBL6991459 | 0.78 | PRKCA (0.42) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL12360855 | 0.76 | PRKCA (0.41) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL6991468 | 0.74 | PRKCA (0.39) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL14681224 | 0.71 | — | — | |
| SCHEMBL15837494 | 0.71 | CYP2C19 (0.34) | POLBGAACYP2C19BLMATM | |
| SCHEMBL7348875 | 0.71 | PRKCA (0.37) | PRKCAPOLBGAANPSR1TKT | |
| SCHEMBL767191 | 0.70 | NAAA (0.40) | POLBGAACYP2C19BLMATM | |
| SCHEMBL14675199 | 0.70 | CYP2C19 (0.33) | POLBCYP2C19BLMATM | |
| SCHEMBL681950 | 0.69 | PRKCA (0.46) | PRKCAPOLBGAANPSR1BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001577-B2 | Pesticidally active azetidine sulfones amide isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-11 | — | — | US | disclosed |
| US-11001577-B2 | Pesticidally active azetidine sulfones amide isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-11 | — | — | US | disclosed |
| EP-3555083-B1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| EP-3555083-B1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| US-20200123143-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-23 | — | — | US | disclosed |
| US-20200123143-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-23 | — | — | US | disclosed |
| EP-3555083-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | Syngenta Participations AG (CH) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018114791-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018114791-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123143-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | ACHE, PRDX1, DDT | PRKCA 2753/4885POLB 4117/4885GAA 2076/4885 |
| US-11001577-B2 | Pesticidally active azetidine sulfones amide isoxazoline derivatives | ACHE, PRDX1, DDT | PRKCA 2753/4885POLB 4117/4885GAA 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.