Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766978 | 0.77 | NAAA (0.44) | NAAAALDH1A1CYP2C19BLMCYP1A2 | |
| SCHEMBL11156847 | 0.75 | — | — | |
| SCHEMBL767174 | 0.74 | ALDH1A1 (0.59) | ALDH1A1CYP2C19BLMCYP1A2LMNA | |
| SCHEMBL14681224 | 0.73 | — | — | |
| SCHEMBL774197 | 0.73 | — | — | |
| SCHEMBL14675199 | 0.71 | CYP2C19 (0.33) | CYP2C19BLMPOLBATM | |
| SCHEMBL7603571 | 0.71 | — | — | |
| SCHEMBL681192 | 0.70 | NAAA (0.52) | NAAAALDH1A1CYP2C19BLMCYP1A2 | |
| SCHEMBL20299385 | 0.70 | PRKCA (0.38) | CYP2C19BLMGAAPOLBATM | |
| SCHEMBL767372 | 0.70 | CHRNB2 (0.45) | CYP2C19BLMPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001577-B2 | Pesticidally active azetidine sulfones amide isoxazoline derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-11 | — | — | US | disclosed |
| EP-3555083-B1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| EP-3555083-B1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| US-20200123143-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-23 | — | — | US | disclosed |
| EP-3555083-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | Syngenta Participations AG (CH) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018114791-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018114791-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
| US-20140179875-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179875-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179875-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| WO-2013017469-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| WO-2013017469-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | GIRINDUS AMERICA, INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| US-20120071640-A1 | Sulfurizing reagents and their use for oligonucleotides synthesis | GIRINDUS AMERICA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071640-A1 | Sulfurizing reagents and their use for oligonucleotides synthesis | GIRINDUS AMERICA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071640-A1 | Sulfurizing reagents and their use for oligonucleotides synthesis | GIRINDUS AMERICA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| EP-2382227-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | Girindus America, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010072831-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | GIRINDUS AMERICA, INC (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010072831-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | GIRINDUS AMERICA, INC (US) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071640-A1 | Sulfurizing reagents and their use for oligonucleotides synthesis | RRM1, SRRT, NSUN2 | NAAA 3077/4885ALDH1A1 3432/4885CYP2C19 3300/4885 |
| US-20200123143-A1 | PESTICIDALLY ACTIVE AZETIDINE SULFONES AMIDE ISOXAZOLINE DERIVATIVES | ACHE, PRDX1, DDT | NAAA 154/4885ALDH1A1 639/4885CYP2C19 56/4885 |
| US-20140179875-A1 | SULFURIZATION REAGENTS ON SOLID SUPPORTS | OR10J3, RPS8, NSUN2 | NAAA 3262/4885ALDH1A1 3730/4885CYP2C19 2327/4885 |
| US-11001577-B2 | Pesticidally active azetidine sulfones amide isoxazoline derivatives | ACHE, PRDX1, DDT | NAAA 154/4885ALDH1A1 639/4885CYP2C19 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.