Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030929 | 1.00 | NFE2L2 (0.35) | NFE2L2SLC22A12ARPTGES2PGR | |
| SCHEMBL18215497 | 0.77 | NFE2L2 (0.38) | NFE2L2SLC22A12PTGES2HSD11B1NFKB1 | |
| SCHEMBL12641533 | 0.77 | NFE2L2 (0.38) | NFE2L2SLC22A12PTGES2HSD11B1NFKB1 | |
| SCHEMBL7484296 | 0.75 | KCNH2 (0.47) | KCNH2MAT2A | |
| SCHEMBL7484292 | 0.75 | KCNH2 (0.47) | KCNH2MAT2A | |
| SCHEMBL5644762 | 0.73 | NFKB1 (0.53) | NFKB1 | |
| SCHEMBL4728560 | 0.73 | NFKB1 (0.53) | NFKB1 | |
| SCHEMBL18215568 | 0.72 | NFE2L2 (0.35) | NFE2L2SLC22A12PTGES2HSD11B1KCNH2 | |
| SCHEMBL9683791 | 0.72 | NFKB1 (0.38) | ARENPP2HSD11B1NFKB1 | |
| SCHEMBL20086556 | 0.72 | P2RX7 (0.37) | NFE2L2SLC22A12ARPTGES2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012175514-A1 | PYRIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-12-27 | — | — | WO | disclosed |
| WO-2011076687-A1 | PYRIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-30 | — | — | WO | disclosed |