Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12631368 | 0.87 | LMNA (0.65) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2033680 | 0.83 | ALDH1A1 (0.57) | GAAALDH1A1LMNACYP2C19MEN1 | |
| SCHEMBL12631366 | 0.83 | ALDH1A1 (0.57) | GAAALDH1A1LMNACYP2C19MEN1 | |
| SCHEMBL2029078 | 0.76 | HTR2B (0.58) | KMT2A | |
| SCHEMBL2019135 | 0.74 | HPGD (0.53) | GAAALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL12631602 | 0.74 | KMT2A (0.60) | GAAALDH1A1LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL2010049 | 0.74 | KMT2A (0.60) | GAAALDH1A1LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL2035987 | 0.73 | APP (0.46) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL12632586 | 0.73 | APP (0.46) | GAAALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL12632585 | 0.73 | ALDH1A1 (0.49) | GAAALDH1A1LMNASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |