Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24488175 | 0.89 | MEN1 (0.35) | MEN1KMT2APDE4BMAPTKDM4E | |
| SCHEMBL21251963 | 0.86 | PDE4B (0.35) | MEN1KMT2APDE4BMAPTKDM4E | |
| SCHEMBL21251874 | 0.79 | FGFR4 (0.35) | MEN1KMT2APDE4BHPGDSMAPT | |
| SCHEMBL20331456 | 0.75 | MEN1 (0.41) | MEN1KMT2APDE4BMAPTKDM4E | |
| SCHEMBL24488264 | 0.73 | P2RX3 (0.36) | KDM4E | |
| SCHEMBL20330599 | 0.72 | MEN1 (0.38) | MEN1KMT2APDE4BMAPT | |
| SCHEMBL24488280 | 0.72 | FGFR1 (0.33) | MEN1KMT2A | |
| SCHEMBL21252130 | 0.68 | THRB (0.36) | MEN1KMT2AHPGDSMAPT | |
| SCHEMBL18981723 | 0.63 | MEN1 (0.39) | MEN1KMT2AMAPT | |
| SCHEMBL21251961 | 0.63 | NFE2L2 (0.33) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018113584-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2018-06-28 | — | — | WO | disclosed |