SCHEMBL20341101

SCHEMBL20341101

COP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)OCC1C[C@@H](O)C(n2cnc3c(=O)[nH]cnc32)O1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 7/20 0.58
▸ P2RX3 P56373 2/20 0.56
▸ P2RY1 P47900 2/20 0.55
▸ SRC P12931 1/20 0.55
▸ P2RY2 P41231 1/20 0.55
▸ P2RX1 P51575 1/20 0.55
▸ P2RX4 Q99571 1/20 0.55
▸ P2RX2 Q9UBL9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21417372 0.94 RNASEL (0.66) RNASELP2RY1SRCP2RY2
SCHEMBL22352060 0.94 RNASEL (0.65) RNASELP2RX3P2RY1SRCP2RY2
SCHEMBL23477159 0.91 RNASEL (0.56) RNASEL
SCHEMBL24771772 0.91 RNASEL (0.56) RNASEL
SCHEMBL23477028 0.90 FUT5 (0.58) RNASELP2RX3P2RY2
SCHEMBL24703982 0.88 RNASEL (0.75) RNASELP2RY1SRCP2RY2
SCHEMBL19696038 0.86 RNASEL (0.61) RNASEL
SCHEMBL16727889 0.86 P2RX3 (0.68) RNASELP2RX3
SCHEMBL18087247 0.86 P2RX3 (0.68) RNASELP2RX3
SCHEMBL25552773 0.86 TGM2 (0.60) RNASELP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011630-B2 Cyclic dinucleotides for cytokine induction INVIVOGEN (FR) 2018-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011630-B2 Cyclic dinucleotides for cytokine induction IL1B, IFNG, IFNAR1 RNASEL 703/4885P2RX3 1368/4885P2RY1 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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