Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029343 | 0.87 | MAPT (0.46) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL5583481 | 0.85 | TSHR (0.40) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5583445 | 0.84 | PKM (0.40) | MAPTRAB9ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL2028883 | 0.81 | LMNA (0.45) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL2034196 | 0.81 | FBP1 (0.40) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL6896387 | 0.80 | ALDH1A1 (0.46) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL5583431 | 0.80 | ALDH1A1 (0.43) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL2033475 | 0.79 | MAPT (0.47) | MAPTRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL5583271 | 0.79 | CYP1A2 (0.48) | MAPTSMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL2034070 | 0.78 | VCAM1 (0.37) | MAPTRAB9ASMN1; SMN2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | claimed |