Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028578 | 0.92 | HCAR3 (0.42) | MAPTAKR1C3AKR1C2MAPK1ALDH1A1 | |
| SCHEMBL2034196 | 0.84 | FBP1 (0.40) | MAPTAKR1C3AKR1C2MAPK1ALDH1A1 | |
| SCHEMBL2029622 | 0.79 | MAPT (0.43) | MAPTAKR1C3AKR1C2MAPK1ALDH1A1 | |
| SCHEMBL2034070 | 0.78 | VCAM1 (0.37) | MAPTALDH1A1TDP1GAAHTT | |
| SCHEMBL2029853 | 0.77 | ALDH1A1 (0.34) | MAPTMAPK1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2034068 | 0.77 | MEN1 (0.37) | MAPTMAPK1ALDH1A1TDP1HTT | |
| SCHEMBL2052797 | 0.77 | HCAR3 (0.38) | MAPTMAPK1ALDH1A1L3MBTL1HTT | |
| SCHEMBL5583481 | 0.76 | TSHR (0.40) | MAPTALDH1A1TDP1L3MBTL1HTT | |
| SCHEMBL5583445 | 0.75 | PKM (0.40) | MAPTMAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2034235 | 0.74 | ABCB1 (0.39) | AKR1C3AKR1C2ALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | claimed |
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | disclosed |
| US-20090270279-A1 | Materials and Methods for the Photodirected Synthesis of Oligonucleotide Arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2009-10-29 | — | — | US | disclosed |
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | disclosed |