SCHEMBL20349265

SCHEMBL20349265

Cc1ccc2c(oc3ncccc32)c1N1c2ccccc2N(c2ccccc2)[C@@H]1C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ PIK3CA P42336 2/20 0.31
▸ CYP1A2 P05177 1/20 0.30
▸ CYP1B1 Q16678 1/20 0.30
▸ SLC6A2 P23975 1/20 0.30
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20697844 1.00 KDM4E (0.32) KDM4EALDH1A1PIK3CACYP1A2CYP1B1
SCHEMBL20349248 0.92 PIK3CA (0.32) PIK3CA
SCHEMBL20349266 0.92 PIK3CA (0.34) PIK3CA
SCHEMBL20349255 0.88 PIK3CA (0.35) KDM4EALDH1A1PIK3CACYP1A2CYP1B1
SCHEMBL23729265 0.87 KDM4E (0.32) KDM4EALDH1A1PIK3CACYP1A2CYP1B1
SCHEMBL16726451 0.87 KDM4E (0.32) KDM4EALDH1A1PIK3CACYP1A2CYP1B1
SCHEMBL20349259 0.86 — —
SCHEMBL25554078 0.86 KDM4E (0.32) KDM4EPIK3CA
SCHEMBL18020955 0.85 PIK3CA (0.31) KDM4EALDH1A1PIK3CACYP1A2CYP1B1
SCHEMBL25705867 0.84 KDM4E (0.35) KDM4EALDH1A1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 — — US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 — — US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 — — US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 — — US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 — — US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 — — US disclosed
US-20190074456-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-07 — — US disclosed
US-20190058136-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-21 — — US disclosed
US-20190051844-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-14 — — US disclosed
US-20190036058-A1 USE OF SINGLET-TRIPLET GAP HOSTS FOR INCREASING STABILITY OF BLUE PHOSPHORESCENT EMISSION UNIVERSAL DISPLAY CORPORATION 2019-01-31 — — US disclosed
US-20190036040-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-01-31 — — US disclosed
US-20190036055-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-01-31 — — US disclosed
EP-3435438-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-01-30 — — EP disclosed
US-20190019963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-01-17 — — US disclosed
US-20180190914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-05 — — US disclosed
US-20180190914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LEF1 KDM4E 3393/4885ALDH1A1 142/4885PIK3CA 4803/4885
US-20190058136-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, OR10J3 KDM4E 3583/4885ALDH1A1 172/4885PIK3CA 4741/4885
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM KDM4E 3774/4885ALDH1A1 330/4885PIK3CA 4714/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR KDM4E 2641/4885ALDH1A1 1200/4885PIK3CA 3873/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND KDM4E 3586/4885ALDH1A1 1948/4885PIK3CA 4369/4885
US-20190036040-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MCU, ICMT, ORAI2 KDM4E 3843/4885ALDH1A1 2712/4885PIK3CA 2518/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 KDM4E 1807/4885ALDH1A1 165/4885PIK3CA 4437/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP KDM4E 4314/4885ALDH1A1 658/4885PIK3CA 4349/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KDM4E 3179/4885ALDH1A1 149/4885PIK3CA 3606/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4507/4885ALDH1A1 175/4885PIK3CA 3838/4885
US-20190051844-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, LBR, YBX1 KDM4E 2064/4885ALDH1A1 1269/4885PIK3CA 4352/4885
US-20180190914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, OCIAD1, ICOSLG KDM4E 3088/4885ALDH1A1 2142/4885PIK3CA 2549/4885
US-20190074456-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, SOD3, L1CAM KDM4E 3336/4885ALDH1A1 1745/4885PIK3CA 3901/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP KDM4E 3813/4885ALDH1A1 128/4885PIK3CA 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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