SCHEMBL2035375

SCHEMBL2035375

O=S(=O)(c1ccc(Cl)cc1)c1cccc(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
CYP3A4 P08684 1/20 0.67
MAPK1 P28482 1/20 0.67
HSD11B1 P28845 1/20 0.58
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HTT P42858 2/20 0.54
LMNA P02545 1/20 0.54
MAPT P10636 2/20 0.51
KDM4E B2RXH2 2/20 0.51
GAA P10253 2/20 0.51
AKR1B1 P15121 1/20 0.50
ABCC9 O60706 1/20 0.50
ABCC8 Q09428 1/20 0.50
KCNJ11 Q14654 1/20 0.50
KCNJ8 Q15842 1/20 0.50
CNR2 P34972 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408747 1.00 ALDH1A1 (0.67) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL10974178 0.96 HSD11B1 (0.61) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL3006195 0.91 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL31435391 0.91 AKR1B1 (0.56) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL2199161 0.91 AKR1B1 (0.56) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL3834491 0.89 HTR6 (0.61) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL8866046 0.86 MEN1 (0.66) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL10926382 0.86 ALDH1A1 (0.59) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL3155458 0.86 PGR (0.61) ALDH1A1CYP3A4MAPK1HSD11B1MEN1
SCHEMBL3446020 0.86 HSD11B1 (0.57) ALDH1A1CYP3A4MAPK1HSD11B1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220371993-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2022-11-24 US claimed
EP-3914584-B1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2022-10-12 EP claimed
CN-114302871-A Crystal Composition (CC) comprising 4, 4' -dichlorodiphenyl sulfone crystals (C) 巴斯夫欧洲公司 2022-04-08 CN claimed
EP-3914584-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2021-12-01 EP claimed
WO-2021037797-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2021-03-04 WO claimed
US-20110218357-A1 PROCESSES FOR PREPARING 4-CHLOROBENZENESULFONIC ACID AND 4,4'-DICHLORODIPHENYL SULFONE BASF SE (DE) 2011-09-08 US claimed
EP-0279387-B1 PROCESS FOR THE SEPARATION OF 4,4'-DICHLORODIPHENYL SULFONE BASF Aktiengesellschaft (DE) 1990-05-02 EP claimed
US-4876390-A ADSORPTION USING TYPE X OR TYPE ZEOLITE UOP (US) 1989-10-24 US claimed
US-4873372-A Isolation of 4,4'-dichlorodiphenyl sulfone BASF AKTIENGESELLSCHAFT (DE) 1989-10-10 US claimed
CN-118234782-A Polyether copolymers based on glycol sugar alcohols 巴斯夫欧洲公司 2024-06-21 CN disclosed
CN-117326990-A Synthesis method of 4,4' -dichlorobenzyl sulfoxide 山东产研高性能材料技术研究院有限公司 2024-01-02 CN disclosed
EP-3741789-B1 AROMATIC POLYSULFONE RESIN AND MEMBRANE THEREOF SUMITOMO CHEMICAL CO (JP) 2023-06-21 EP disclosed
CN-111601838-B Aromatic polysulfone resin and membrane thereof 住友化学株式会社 2023-06-02 CN disclosed
WO-2023084062-A1 POLYARYLETHER COPOLYMERS BASED ON DIOL SUGAR ALCOHOLS BASF SE (DE) 2023-05-19 WO disclosed
US-5342920-A Reacting alkali metal sulfide with dihaloaromatic compound in organic amide solvent, gaseous phase is cooled to condense and refluxed TONEN CHEMICAL CORPORATION (JP) 1994-08-30 US disclosed
EP-0598449-A2 Process for controlling a particle size of polyarylene sulfide and polyarylene sulfide thus produced Tonen Chemical Corporation (JP) 1994-05-25 EP disclosed
EP-0547718-A2 Process for the preparation of polyarylene sulfide and an apparatus for the preparation thereof Tonen Chemical Corporation (JP) 1993-06-23 EP disclosed
US-4873372-A Isolation of 4,4'-dichlorodiphenyl sulfone BASF AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed
US-4873372-A Isolation of 4,4'-dichlorodiphenyl sulfone BASF AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed
US-4482742-A CATALYTIC REDUCING AND DEHALOGENATION 3,3*-DINTITRODIPHENYLSULFONE MITSUI TOATSU CHEMICALS INC. (JP) 1984-11-13 US disclosed