Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974178 | 0.90 | HSD11B1 (0.61) | PGRGAAHSD11B1HTTABCC9 | |
| SCHEMBL2035375 | 0.86 | ALDH1A1 (0.67) | PGRGAAHSD11B1HTTABCC9 | |
| SCHEMBL29408747 | 0.86 | ALDH1A1 (0.67) | PGRGAAHSD11B1HTTABCC9 | |
| SCHEMBL31435391 | 0.86 | AKR1B1 (0.56) | PGRHSD11B1ABCC9ABCC8KCNJ11 | |
| SCHEMBL2199161 | 0.86 | AKR1B1 (0.56) | PGRHSD11B1ABCC9ABCC8KCNJ11 | |
| SCHEMBL3834491 | 0.84 | HTR6 (0.61) | PGRHSD11B1ABCC9ABCC8KCNJ11 | |
| SCHEMBL6151129 | 0.82 | GAA (0.67) | GAAHTTTDP1ABCC9ABCC8 | |
| SCHEMBL31038387 | 0.82 | GAA (0.67) | GAAHTTTDP1ABCC9ABCC8 | |
| SCHEMBL8866046 | 0.81 | MEN1 (0.66) | PGRHSD11B1ABCC9ABCC8KCNJ11 | |
| SCHEMBL3446020 | 0.81 | HSD11B1 (0.57) | PGRHSD11B1ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580164-A | Preparation method of sulfoxide derivative | 华侨大学 | 2024-09-03 | — | — | CN | disclosed |
| EP-1334956-B1 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL CO (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-6916938-B2 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20030171589-A1 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-09-11 | — | — | US | disclosed |
| EP-1334956-A2 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171589-A1 | Method for preparing sulfone or sulfoxide compound | TST, SDHB, GPX4 | PGR 1604/4885GAA 3218/4885HSD11B1 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.