SCHEMBL20354564

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24123778	0.83	ADRB1 (0.50)	MAPTALDH1A1GAAKDM4EKMT2A
	SCHEMBL18937140	0.82	MAPT (0.59)	MAPTALDH1A1GAAGFERKDM4E
	SCHEMBL13724583	0.79	MAPT (0.55)	MAPTALDH1A1GAAGFERKDM4E
	SCHEMBL25675659	0.79	HSD11B1 (0.46)	MAPTALDH1A1GAAKDM4EHTT
	SCHEMBL21526576	0.76	SIRT6 (0.61)	MAPTALDH1A1KMT2AMEN1POLB
	SCHEMBL29225028	0.76	GFER (0.46)	MAPTALDH1A1GAAGFERKDM4E
	SCHEMBL22465998	0.76	MAPT (0.50)	MAPTALDH1A1GAAGFERKDM4E
	SCHEMBL14320742	0.76	MAPT (0.60)	MAPTALDH1A1GAAGFERKDM4E
	SCHEMBL7043679	0.75	MAPT (0.77)	MAPTALDH1A1GAAGFERKDM4E
	SCHEMBL6151120	0.75	MAPT (0.77)	MAPTALDH1A1GAAGFERKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.