SCHEMBL20356381

SCHEMBL20356381

Cc1cc(C)cc(-c2nccc3cc(CC(C)C)ccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ROCK1 Q13464 7/20 0.39
KDM4E B2RXH2 2/20 0.37
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
WNT3A P56704 2/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
SCN9A Q15858 1/20 0.33
ABCB11 O95342 1/20 0.33
ABL1 P00519 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
ROCK2 O75116 1/20 0.32
KCNH2 Q12809 1/20 0.32
DHODH Q02127 1/20 0.32
XDH P47989 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24795726 0.89 ROCK1 (0.34) ROCK1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL13389172 0.89 KDM4E (0.37) ROCK1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL20356272 0.89 ROCK1 (0.39) ROCK1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL20809425 0.88 MAPK14 (0.39) ROCK1KDM4EPOLBSMN1; SMN2SCN9A
SCHEMBL21448977 0.85 MEN1 (0.37) ROCK1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL20809427 0.84 ROCK1 (0.41) ROCK1KDM4ESMN1; SMN2KMT2AABCB11
SCHEMBL21448965 0.84 MEN1 (0.40) ROCK1SMN1; SMN2MEN1KMT2AWNT3A
SCHEMBL25443020 0.83 ROCK1 (0.35) ROCK1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL25443066 0.83 ROCK1 (0.35) ROCK1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL20809339 0.82 SCN9A (0.41) ROCK1MEN1KMT2AWNT3ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
WO-2023221346-A1 ORGANOMETALLIC COMPOUND AND USE THEREOF, LIGHT-EMITTING DEVICE AND LIGHT-EMITTING APPARATUS 吉林奥来德光电材料股份有限公司 2023-11-23 WO disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11753427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-11758804-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
WO-2022262662-A1 ORGANOMETALLIC COMPOUND, AND APPLICATION THEREOF 四川阿格瑞新材料有限公司 2022-12-22 WO disclosed
WO-2022262309-A1 ORGANOMETALLIC IRIDIUM COMPOUND AND APPLICATION THEREOF 广东阿格蕾雅光电材料有限公司 2022-12-22 WO disclosed
US-11437591-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-09-06 US disclosed
US-20220165969-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-05-26 US disclosed
US-11239434-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190312218-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2019-10-10 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed
WO-2018124697-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2018-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 ROCK1 4827/4885KDM4E 4362/4885POLB 3397/4885
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM ROCK1 2411/4885KDM4E 807/4885POLB 1168/4885
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM ROCK1 4210/4885KDM4E 3774/4885POLB 1390/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 ROCK1 4827/4885KDM4E 4362/4885POLB 3397/4885
US-11239434-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM ROCK1 4035/4885KDM4E 3656/4885POLB 1331/4885
US-11758804-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 ROCK1 4015/4885KDM4E 4556/4885POLB 1218/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR ROCK1 2164/4885KDM4E 1788/4885POLB 2770/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 ROCK1 4293/4885KDM4E 3879/4885POLB 3510/4885
US-20220165969-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM ROCK1 2440/4885KDM4E 612/4885POLB 1487/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ROCK1 2057/4885KDM4E 3068/4885POLB 3223/4885
US-20190312218-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, L1CAM ROCK1 2440/4885KDM4E 612/4885POLB 1487/4885
US-11753427-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 ROCK1 3450/4885KDM4E 4607/4885POLB 1025/4885
US-11437591-B2 Organic electroluminescent materials and devices OCIAD2, EML4, KCNJ2 ROCK1 4513/4885KDM4E 2374/4885POLB 2049/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR ROCK1 1384/4885KDM4E 1316/4885POLB 3368/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR ROCK1 2164/4885KDM4E 1788/4885POLB 2770/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP ROCK1 3776/4885KDM4E 3813/4885POLB 1242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.