Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037804 | 0.89 | F9 (0.36) | GRIA1CACNG8PGRBACE1CTSD | |
| SCHEMBL869032 | 0.84 | EDNRB (0.37) | CNR2SLC6A3CTSD | |
| SCHEMBL14983792 | 0.83 | DGAT1 (0.36) | GRIA1CACNG8PGRDGAT1 | |
| SCHEMBL3026367 | 0.82 | PGR (0.39) | CNR2GRIA1CACNG8PGR | |
| SCHEMBL867844 | 0.80 | FASN (0.38) | BACE1CTSD | |
| SCHEMBL14983793 | 0.78 | SIGMAR1 (0.38) | PGR | |
| SCHEMBL14983763 | 0.76 | BACE1 (0.38) | PGRAPPBACE1 | |
| SCHEMBL12632679 | 0.73 | FASN (0.35) | BACE1CTSD | |
| SCHEMBL412386 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL418343 | 0.70 | FFAR1 (0.40) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073616-A2 | HERBICIDAL COMPOSITIONS COMPRISING, AND METHODS OF USE OF, HERBICIDALLY ACTIVE PYRANDIONES | SYNGENTA LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |