Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 4/20 | 0.36 |
| ▸ | F11 | P03951 | 4/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036052 | 0.89 | CNR2 (0.38) | PGRCTSDBACE1GRIA1CACNG8 | |
| SCHEMBL867844 | 0.82 | FASN (0.38) | KLKB1CTSDBACE1 | |
| SCHEMBL869032 | 0.82 | EDNRB (0.37) | CTSD | |
| SCHEMBL14983792 | 0.81 | DGAT1 (0.36) | PGRGRIA1CACNG8PLAT | |
| SCHEMBL3026367 | 0.80 | PGR (0.39) | PGRGRIA1CACNG8BRD4 | |
| SCHEMBL14983763 | 0.79 | BACE1 (0.38) | KLKB1PGRBACE1 | |
| SCHEMBL14983793 | 0.76 | SIGMAR1 (0.38) | PGRBRD4 | |
| SCHEMBL12632679 | 0.76 | FASN (0.35) | KLKB1CTSDBACE1 | |
| SCHEMBL412386 | 0.72 | ALDH1A1 (0.38) | BRD4 | |
| SCHEMBL418343 | 0.70 | FFAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073616-A2 | HERBICIDAL COMPOSITIONS COMPRISING, AND METHODS OF USE OF, HERBICIDALLY ACTIVE PYRANDIONES | SYNGENTA LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |