Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887378 | 1.00 | ALDH1A1 (0.43) | ALDH1A1DGKATSHRLMNANFKB1 | |
| SCHEMBL14938147 | 0.97 | ALDH1A1 (0.46) | ALDH1A1DGKATSHRLMNANFKB1 | |
| SCHEMBL28812961 | 0.89 | DGKA (0.57) | ALDH1A1DGKATSHRLMNAPAM | |
| SCHEMBL27238986 | 0.89 | DGKA (0.57) | ALDH1A1DGKATSHRLMNAPAM | |
| SCHEMBL3173473 | 0.88 | ALDH1A1 (0.48) | ALDH1A1DGKATSHRLMNAPRSS1 | |
| SCHEMBL25304019 | 0.85 | ALDH1A1 (0.54) | ALDH1A1DGKATSHRLMNAPAM | |
| SCHEMBL27277210 | 0.85 | PTGS1 (0.41) | ALDH1A1DGKATSHRLMNAPAM | |
| SCHEMBL27895346 | 0.85 | MGAM (0.43) | ALDH1A1DGKATSHRLMNAPAM | |
| SCHEMBL4924469 | 0.81 | DGKA (0.38) | ALDH1A1DGKATSHRLMNANFKB1 | |
| SCHEMBL18009957 | 0.81 | DGKA (0.48) | ALDH1A1DGKATSHRLMNAPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240191032-A1 | MECHANOCHROMISM AND STRAIN-INDUCED CRYSTALLIZATION IN THIOL-YNE-DERIVED STEREOELASTOMERS | UNIV DUKE (US) | 2024-06-13 | — | — | US | claimed |
| US-20240191032-A1 | MECHANOCHROMISM AND STRAIN-INDUCED CRYSTALLIZATION IN THIOL-YNE-DERIVED STEREOELASTOMERS | UNIV DUKE (US) | 2024-06-13 | — | — | US | disclosed |
| US-20180044362-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044362-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | MGMT, DPYD, OGG1 | ALDH1A1 340/4885DGKA 3257/4885TSHR 4229/4885 |
| US-20240191032-A1 | MECHANOCHROMISM AND STRAIN-INDUCED CRYSTALLIZATION IN THIOL-YNE-DERIVED STEREOELASTOMERS | TST, SPR, PIEZO1 | ALDH1A1 1742/4885DGKA 4297/4885TSHR 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.