Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.41 |
| ▸ | TUBB | P07437 | 4/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899630 | 0.79 | ALDH1A1 (0.52) | CYP3A4CYP1A1CYP1B1KDM4EALDH1A1 | |
| SCHEMBL3751505 | 0.78 | ALDH1A1 (0.59) | ACHECYP3A4MAPTCA9TUBB1 | |
| SCHEMBL1480652 | 0.78 | CYP1A1 (0.53) | MAPTCYP1A1CYP1B1KDM4EALDH1A1 | |
| SCHEMBL8348600 | 0.78 | CYP19A1 (0.44) | ACHECYP3A4MAPTCA9TUBB4A | |
| SCHEMBL14965876 | 0.77 | PDE4A (0.40) | ACHECYP3A4MAPTCA9TUBB4A | |
| SCHEMBL22991671 | 0.77 | MCL1 (0.43) | — | |
| Isoallyltetramethoxybenzene SCHEMBL28541950 | 0.77 | CYP3A4 (0.61) | ACHECYP3A4MAPTCA9TUBB4A | |
| SCHEMBL679526 | 0.75 | ACHE (0.60) | ACHECYP3A4MAPTCA9TUBB4A | |
| SCHEMBL28768613 | 0.75 | TUBB4A (0.42) | ACHECYP3A4MAPTCA9TUBB4A | |
| SCHEMBL8563051 | 0.75 | ALDH1A1 (0.48) | ACHEMAPTCA9TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702251-A | Detection of advanced adenomas and/or early colorectal cancer | 通用诊断公司 | 2023-02-14 | — | — | CN | disclosed |
| US-10246536-B2 | Functionalized highly syndiotactic polystyrene and preparation method thereof | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2019-04-02 | — | — | US | disclosed |
| US-20170335036-A1 | FUNCTIONALIZED HIGHLY SYNDIOTACTIC POLYSTYRENE AND PREPARATION METHOD THEREOF | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-23 | — | — | US | disclosed |
| US-20170335036-A1 | FUNCTIONALIZED HIGHLY SYNDIOTACTIC POLYSTYRENE AND PREPARATION METHOD THEREOF | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-23 | — | — | US | disclosed |
| US-9551712-B2 | Volatile organic compounds as diagnostic markers for various types of cancer | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2017-01-24 | — | — | US | disclosed |
| EP-2330173-B1 | A RADIAL TYPE LIQUID CRYSTAL COMPOUND, AND AN OPTICAL FILM AND LIQUID CRYSTAL DISPLAY (LCD) DEVICE CONTAINING COMPOUND | LG CHEMICAL LTD (KR) | 2016-08-17 | — | — | EP | disclosed |
| US-20120326092-A1 | VOLATILE ORGANIC COMPOUNDS AS DIAGNOSTIC MARKERS FOR VARIOUS TYPES OF CANCER | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2012-12-27 | — | — | US | disclosed |
| US-8339567-B2 | Radial-shaped liquid crystal compound, and optical film and liquid crystal display device comprising the same | LG CHEM, LTD. (KR) | 2012-12-25 | — | — | US | disclosed |
| US-20110181826-A1 | RADIAL-SHAPED LIQUID CRYSTAL COMPOUND, AND OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2011-07-28 | — | — | US | disclosed |
| EP-2330173-A2 | A RADIAL TYPE LIQUID CRYSTAL COMPOUND, AND AN OPTICAL FILM AND LIQUID CRYSTAL DISPLAY (LCD) DEVICE CONTAINING COMPOUND | LG Chem, Ltd. (KR) | 2011-06-08 | — | — | EP | disclosed |
| CN-1561215-A | Salts of substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid compounds used as nmda antagonist | GRUENENTHAL GMBH (DE) | 2005-01-05 | — | — | CN | disclosed |
| US-20040224969-A1 | Salts of substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid compounds | GRUENENTHAL GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
| US-6699877-B2 | TREATING PAIN, MIGRAINE, AND VARIOUS OTHER DISEASES | GRUENENTHAL GMBH (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030087926-A1 | Substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid derivatives | GRUENENTHAL GMBH | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087926-A1 | Substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid derivatives | SDHA, CACNA1A, GRIN2C | ACHE 158/4885CYP3A4 207/4885MAPT 1450/4885 |
| US-20110181826-A1 | RADIAL-SHAPED LIQUID CRYSTAL COMPOUND, AND OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME | CXCR1, NLRP1, RCC1 | ACHE 3076/4885CYP3A4 2002/4885MAPT 213/4885 |
| US-20040224969-A1 | Salts of substituted 1,2,3,4-tetrahydroquinoline-2-carboxylic acid compounds | OPRK1, SDHA, GRIN2C | ACHE 291/4885CYP3A4 90/4885MAPT 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.