Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655113 | 0.88 | POLB (0.57) | RAB9APOLBNR4A1MAPTHSD17B10 | |
| SCHEMBL20782749 | 0.87 | KIF11 (0.49) | RAB9APOLBMAPTHSD17B10ALDH1A1 | |
| SCHEMBL1689404 | 0.80 | HDAC3 (0.62) | RAB9APOLBNR4A1HSD17B10ALDH1A1 | |
| SCHEMBL2633385 | 0.79 | ALDH1A1 (0.58) | RAB9APOLBNR4A1HSD17B10ALDH1A1 | |
| SCHEMBL23251079 | 0.78 | ALDH1A1 (0.48) | RAB9APOLBNR4A1MAPTHSD17B10 | |
| SCHEMBL20372223 | 0.77 | ALDH1A1 (0.40) | MAPTALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL18672955 | 0.76 | KCNJ6 (0.49) | RAB9APOLBNR4A1MAPTL3MBTL1 | |
| SCHEMBL21652254 | 0.76 | KIF11 (0.47) | POLBMAPTALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL21998702 | 0.76 | NR3C2 (0.51) | MAPTCYP1A2SMN1; SMN2LMNA | |
| SCHEMBL505220 | 0.76 | RXFP1 (0.69) | RAB9AMAPTALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
| US-20180194757-A1 | NEPRILYSIN INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | RAB9A 4007/4885POLB 1840/4885NR4A1 809/4885 |
| US-20180194757-A1 | NEPRILYSIN INHIBITORS | MME, REN, ACE | RAB9A 2069/4885POLB 3034/4885NR4A1 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.