Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030265 | 0.95 | ALDH1A1 (0.31) | TSHRL3MBTL1 | |
| SCHEMBL2062628 | 0.79 | FNTA (0.49) | TSHRFAAHDGKAMEN1KMT2A | |
| SCHEMBL2036704 | 0.75 | TSHR (0.49) | TSHREPHX1 | |
| SCHEMBL28445116 | 0.75 | PRSS1 (0.38) | TSHRFAAHDGKAPRSS1PRSS2 | |
| SCHEMBL15976529 | 0.73 | DGKA (0.65) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL10384378 | 0.72 | GAA (0.41) | FAAHKMT2AL3MBTL1 | |
| SCHEMBL2030267 | 0.72 | ACHE (0.47) | TSHRTHRB | |
| SCHEMBL9569406 | 0.72 | DGKA (0.61) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| Hexanoate SCHEMBL28009757 | 0.71 | TSHR (0.53) | TSHRMEN1KMT2ATHRB | |
| SCHEMBL15169971 | 0.70 | CHRM5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| CN-105567260-B | Functionalized photoreactive compounds | 罗利克有限公司 | 2018-09-11 | — | — | CN | disclosed |
| EP-3004050-A1 | CYANOSTILBENES | Rolic AG (CH) | 2016-04-13 | — | — | EP | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| WO-2014191292-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2014-12-04 | — | — | WO | disclosed |
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| EP-1928979-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1764405-A1 | Functionalized photoreactive compounds | Rolic AG (CH) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | TSHR 4847/4885FAAH 1154/4885DGKA 3163/4885 |
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | TSHR 4718/4885FAAH 4275/4885DGKA 3670/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | TSHR 4718/4885FAAH 4275/4885DGKA 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.