Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037350 | 1.00 | NOD1 (0.43) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL29588653 | 0.92 | NOD1 (0.48) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL30304076 | 0.92 | NOD1 (0.48) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL28485859 | 0.92 | CA2 (0.41) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL20813966 | 0.87 | NOD1 (0.42) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL31321524 | 0.86 | GPR84 (0.44) | NOD1GPR84FFAR1PPARDPPARG | |
| SCHEMBL19852728 | 0.86 | GPR84 (0.44) | NOD1GPR84FFAR1PPARDPPARG | |
| SCHEMBL19852729 | 0.86 | NOD1 (0.41) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL20813983 | 0.84 | PLA2G2A (0.41) | NOD1GPR84FFAR1PPARDMAPT | |
| SCHEMBL12156898 | 0.84 | FDPS (0.39) | GRIK1GRIK2CA2MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9220799-B2 | Bactericidal agent composition | SUNSTAR ENGINEERING INC. (JP) | 2015-12-29 | — | — | US | claimed |
| WO-2024143126-A1 | ORAL COMPOSITION | サンスター株式会社 | 2024-07-04 | — | — | WO | disclosed |
| US-20240058251-A1 | Composition for Oral Cavity | SUNSTAR SUISSE SA (CH) | 2024-02-22 | — | — | US | disclosed |
| EP-4268828-A1 | COMPOSITION FOR ORAL CAVITY | Sunstar Suisse SA (CH) | 2023-11-01 | — | — | EP | disclosed |
| CN-116669693-A | Oral composition | 盛势达（瑞士）有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022145325-A1 | COMPOSITION FOR ORAL CAVITY | サンスター スイス エスエー | 2022-07-07 | — | — | WO | disclosed |
| EP-3223791-B1 | ORAL CARE COMPOSITIONS HAVING HIGH WATER CONTENT AND MICRO ROBUSTNESS | COLGATE PALMOLIVE CO (US) | 2022-03-09 | — | — | EP | disclosed |
| CN-106999405-B | Oral care compositions with high water content and little robustness | 高露洁-棕榄公司 | 2020-07-10 | — | — | CN | disclosed |
| US-10206860-B2 | Biguanide preservation of precipitated calcium carbonate | COLGATE-PALMOLIVE COMPANY (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170333330-A1 | Oral Care Compositions Having High Water Content and Micro Robustness | COLGATE-PALMOLIVE COMPANY (US) | 2017-11-23 | — | — | US | disclosed |
| US-20120276023-A1 | BIGUANIDE PRESERVATION OF PRECIPITATED CALCIUM CARBONATE | COLGATE-PALMOLIVE COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| EP-2512407-A2 | POLYMERIC BIGUANIDE PRESERVATION OF PRECIPITATED CALCIUM CARBONATE | Colgate-Palmolive Company (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075662-A2 | BIGUANIDE PRESERVATION OF PRECIPITATED CALCIUM CARBONATE | COLGATE-PALMOLIVE COMPANY (US) | 2011-06-23 | — | — | WO | disclosed |
| US-20100034871-A1 | Center-Filled Chewing Gum Product For Dental Care | GUMLINK A/S (DK) | 2010-02-11 | — | — | US | disclosed |
| EP-2136648-A1 | CENTER-FILLED CHEWING GUM PRODUCT FOR DENTAL CARE | Gumlink A/S (DK) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008122286-A1 | CENTER-FILLED CHEWING GUM PRODUCT FOR DENTAL CARE | GUMLINK A/S (DK) | 2008-10-16 | — | — | WO | disclosed |
| US-20070187429-A1 | Dual opening tubular dispenser | FARAHMAND BARDIA | 2007-08-16 | — | — | US | disclosed |
| WO-2000069401-A1 | METHOD FOR THE MANUFACTURE OF TOOTHPASTE | COLGATE-PALMOLIVE COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| US-6149894-A | MIXING TOGETHER A HIGH SOLIDS CALCIUM CARBONATE ABRASIVE DISPERSION AND AN AQUEOUS HUMECTANT PRIOR TO ADDING A THICKENER | COLGATE PALMOLIVE COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| US-5882631-A | Oral composition | SUNSTAR INC. (JP) | 1999-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206860-B2 | Biguanide preservation of precipitated calcium carbonate | CACNA1C, CA2, KCNN3 | NOD1 4003/4885GPR84 3022/4885FFAR1 2257/4885 |
| US-20120276023-A1 | BIGUANIDE PRESERVATION OF PRECIPITATED CALCIUM CARBONATE | CACNA1C, CA2, KCNN3 | NOD1 4003/4885GPR84 3022/4885FFAR1 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.