SCHEMBL20378784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1007940	0.83	HDAC6 (0.50)	MMP2PPARGBCHEHDAC6HDAC1
	SCHEMBL18073570	0.83	HDAC6 (0.50)	MMP2PPARGBCHEHDAC6HDAC1
	SCHEMBL5170269	0.83	HDAC6 (0.50)	MMP2PPARGBCHEHDAC6HDAC1
	SCHEMBL17598200	0.82	MMP14 (0.50)	MMP2PPARGBCHEHDAC6HDAC1
	SCHEMBL1006764	0.79	LMNA (0.49)	MMP2PPARGBCHEHDAC6
	SCHEMBL17037834	0.79	SIGMAR1 (0.52)	PPARGBCHE
	SCHEMBL31478349	0.78	LMNA (0.50)	MMP2PPARGBCHEHDAC6
	SCHEMBL31478350	0.78	LMNA (0.50)	MMP2PPARGBCHEHDAC6
	SCHEMBL31478356	0.78	LMNA (0.50)	MMP2PPARGBCHEHDAC6
	SCHEMBL28335477	0.78	BCHE (0.45)	MMP2PPARGBCHETP53L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.