Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137818 | 0.83 | CES2 (0.49) | KMT2AMEN1MAPK14 | |
| SCHEMBL4139690 | 0.81 | HSD17B14 (0.54) | KMT2AMEN1MAPK14ALDH1A1MAPT | |
| SCHEMBL7824045 | 0.80 | AKR1C3 (0.62) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL7850570 | 0.80 | AKR1C3 (0.62) | KMT2AMEN1KDM4CKDM4DAKR1C3 | |
| SCHEMBL29578794 | 0.79 | KDM4C (0.59) | KMT2AMEN1KDM4CKDM4DALDH1A1 | |
| SCHEMBL82604 | 0.79 | KDM4C (0.59) | KMT2AMEN1KDM4CKDM4DALDH1A1 | |
| SCHEMBL1643213 | 0.79 | ALDH1A1 (0.65) | KMT2AMEN1KDM4CKDM4DMAPK14 | |
| SCHEMBL8693095 | 0.79 | KMT2A (0.55) | KMT2AMEN1KDM4CKDM4DMAPK14 | |
| SCHEMBL7404189 | 0.78 | KMT2A (0.59) | KMT2AMEN1MAPK14ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL16703122 | 0.77 | ALDH1A1 (0.62) | KMT2AMEN1KDM4CKDM4DMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265613-A1 | BENZENE RING COMPOUND AND USE THEREOF | Nanjing Shijiang Medicine Technology Co., Ltd (CN) | 2023-10-25 | — | — | EP | disclosed |
| WO-2018130227-A1 | AROMATIC RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 山东罗欣药业集团股份有限公司 | 2018-07-19 | — | — | WO | disclosed |