Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346542 | 0.88 | MGLL (0.33) | MGLL | |
| SCHEMBL20395925 | 0.87 | USP2 (0.39) | — | |
| SCHEMBL2422488 | 0.74 | RORC (0.41) | — | |
| SCHEMBL18812823 | 0.72 | BACE1 (0.35) | MGLL | |
| SCHEMBL7700874 | 0.72 | HSD11B1 (0.31) | — | |
| SCHEMBL2422490 | 0.71 | DRD2 (0.31) | — | |
| SCHEMBL308840 | 0.71 | BACE1 (0.30) | — | |
| SCHEMBL18153985 | 0.70 | BACE1 (0.30) | — | |
| SCHEMBL31570420 | 0.70 | — | — | |
| SCHEMBL12481520 | 0.69 | OPRD1 (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134695-A1 | 1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS | PFIZER INC. (US) | 2018-07-26 | — | — | WO | disclosed |