Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20399809 | 0.88 | MGLL (0.32) | MGLL | |
| SCHEMBL2422488 | 0.86 | RORC (0.41) | RORC | |
| SCHEMBL31387182 | 0.82 | — | — | |
| SCHEMBL20395925 | 0.75 | USP2 (0.39) | RORC | |
| SCHEMBL2422490 | 0.73 | DRD2 (0.31) | — | |
| SCHEMBL18812823 | 0.72 | BACE1 (0.35) | MGLL | |
| SCHEMBL20412573 | 0.72 | GPR119 (0.40) | RORC | |
| SCHEMBL12481520 | 0.71 | OPRD1 (0.39) | MGLL | |
| SCHEMBL308840 | 0.70 | BACE1 (0.30) | — | |
| SCHEMBL12543469 | 0.69 | HSD11B1 (0.34) | MGLLRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134695-A1 | 1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS | PFIZER INC. (US) | 2018-07-26 | — | — | WO | disclosed |
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |