Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15100855 | 0.89 | MGLL (0.50) | LMNAHSD17B10ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL18634077 | 0.86 | LMNA (0.44) | LMNAHSD17B10ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20408695 | 0.84 | GAA (0.56) | LMNAALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL20408697 | 0.81 | KMT2A (0.57) | LMNAALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL20408696 | 0.79 | GPR183 (0.52) | LMNASMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL20408703 | 0.79 | PKM (0.65) | LMNAALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL20408701 | 0.76 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2GAAHPGDHTT | |
| SCHEMBL18701958 | 0.76 | EPHX2 (0.49) | LMNAHSD17B10ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL15830167 | 0.76 | ALDH1A1 (0.53) | LMNAHSD17B10ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5369302 | 0.75 | CYP3A4 (0.59) | LMNAALDH1A1SMN1; SMN2TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | LMNA 4712/4885HSD17B10 1408/4885ALDH1A1 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.