Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20427981 | 0.84 | CNR2 (0.38) | CNR2LNPEPS1PR4S1PR1S1PR3 | |
| SCHEMBL20427997 | 0.84 | CNR2 (0.34) | CNR2CNR1 | |
| SCHEMBL20428001 | 0.81 | LOXL2 (0.48) | LOXLOXL2CNR2LNPEPS1PR4 | |
| SCHEMBL20428004 | 0.80 | ALDH1A1 (0.46) | S1PR4S1PR1S1PR3S1PR5KDM4E | |
| SCHEMBL27902689 | 0.80 | RECQL (0.52) | RECQLLOXLOXL3LOXL2KDM4E | |
| SCHEMBL27672336 | 0.80 | RECQL (0.52) | RECQLLOXLOXL3LOXL2KDM4E | |
| SCHEMBL27878725 | 0.80 | RECQL (0.52) | RECQLLOXLOXL3LOXL2KDM4E | |
| SCHEMBL20428034 | 0.80 | HPGD (0.36) | CNR2LNPEPS1PR4S1PR1S1PR3 | |
| SCHEMBL4074777 | 0.78 | RECQL (0.53) | RECQLLOXLOXL3LOXL2LNPEP | |
| SCHEMBL20428014 | 0.77 | KCNH2 (0.46) | S1PR4S1PR1S1PR3S1PR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035790-B2 | RORγ modulators | RORB, RORA, RORC | RECQL 665/4885LOX 2925/4885LOXL3 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.