SCHEMBL4433309

SCHEMBL4433309

C[Si](C)(C)N(C(N)=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.41
ALOX5 P09917 2/20 0.40
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 3/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 2/20 0.38
POLB P06746 2/20 0.38
PARP1 P09874 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 5/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 2/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7938546 0.83 NPSR1 (0.50) NPSR1ALDH1A1TSHRGLACYP3A4
SCHEMBL8387202 0.81 NPSR1 (0.43) NPSR1ALDH1A1TSHRGLAMAPT
SCHEMBL9468244 0.78 KDM4E (0.49) NPSR1ALDH1A1TSHRPOLBTDP1
SCHEMBL9623703 0.78 NPSR1 (0.45) NPSR1ALDH1A1TSHRGLACYP3A4
SCHEMBL22680922 0.76 ALDH1A1 (0.46) NPSR1ALDH1A1TSHRGLACYP3A4
SCHEMBL9804578 0.76 KMT2A (0.42) NPSR1ALDH1A1TSHRGLAMAPT
SCHEMBL11742976 0.76 L3MBTL1 (0.40) NPSR1ALDH1A1TSHRGLAMAPT
SCHEMBL25166823 0.75 L3MBTL1 (0.39) NPSR1ALDH1A1TSHRGLAMAPT
SCHEMBL27979600 0.75 KMT2A (0.38) NPSR1ALDH1A1TSHRGLAMAPT
SCHEMBL681204 0.73 MEN1 (0.56) NPSR1ALDH1A1TSHRMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6777026-B2 FILM FORMING ELASTOMER, A ROOM TEMPERATURE CURING AGENT, AND THERMALLY CONDUCTIVE METAL PARTICLES; PROTECTIVE LORD CORPORATION 2004-08-17 US claimed
EP-2010386-A2 INTERLAYERS COMPRISING STABLE INFRARED ABSORBING AGENTS Solutia Incorporated (US) 2009-01-07 EP disclosed
US-7405865-B2 Liquid for electrophoretic display, display medium and display device using the same MITSUBISHI PENCIL CO., LTD. (JP) 2008-07-29 US disclosed
US-20070248809-A1 Interlayers Comprising Stable Infrared Absorbing Agents DEUTSCHE BANK TRUST COMPANY AMERICAS, AS COLLATERAL AGENT 2007-10-25 US disclosed
WO-2007121079-A2 INTERLAYERS COMPRISING HYDROLYTICALLY STABLE INFRARED ABSORBING AGENTS SOLUTIA INCORPORATED (US) 2007-10-25 WO disclosed
US-7244376-B2 Hexaboride particles, hexaboride particle dispersion, and article making use of hexaboride particles or hexaboride particle dispersion SUMITOMO METAL MINING CO., LTD. (JP) 2007-07-17 US disclosed
US-20070002427-A1 Liquid for electrophoretic display and display medium and display employing it MITSUBISHI PENCIL CO., LTD. (JP) 2007-01-04 US disclosed
CN-1846165-A Liquid for electrophoretic display, display medium using the same, and display device MITSUBISHI PENCIL CO (JP) 2006-10-11 CN disclosed
EP-1669798-A1 LIQUID FOR ELECTROPHORETIC DISPLAY AND DISPLAY MEDIUM AND DISPLAY EMPLOYING IT Mitsubishi Pencil Co., Ltd. (JP) 2006-06-14 EP disclosed
US-6972314-B2 OH-containing polysiloxane; carbodiimide; organosilicon crosslinking agent; cured rubber with a higher elongation percentage and improved heat, oil and chemical resistance; automobile applications HENKEL CORPORATION (US) 2005-12-06 US disclosed
WO-2004033573-A9 FLEXIBLE EMISSIVE COATINGS FOR ELASTOMER SUBSTRATES LORD CORP (US) 2005-01-13 WO disclosed
US-6777026-B2 FILM FORMING ELASTOMER, A ROOM TEMPERATURE CURING AGENT, AND THERMALLY CONDUCTIVE METAL PARTICLES; PROTECTIVE LORD CORPORATION 2004-08-17 US disclosed
US-20040127669-A1 Silicone resin composition HENKEL LOCTITE CORPORATION 2004-07-01 US disclosed
WO-2004033573-A1 FLEXIBLE EMISSIVE COATINGS FOR ELASTOMER SUBSTRATES LORD CORPORATION (US) 2004-04-22 WO disclosed
US-20040068036-A1 Flexible emissive coatings for elastomer substrates LORD CORPORATION 2004-04-08 US disclosed
US-6400492-B1 Electrophoretic display liquid, and electrophoretic display medium, method and device using the liquid RICOH COMPANY LIMITED (JP) 2002-06-04 US disclosed
EP-0661358-B1 COATING RESIN COMPOSITION ASAHI GLASS CO LTD (JP) 2000-03-29 EP disclosed
US-5895713-A SILANE SURFACTANT, TETRAALKOXYSILANE OR OLIGOMER ASAHI GLASS COMPANY LTD. (JP) 1999-04-20 US disclosed
US-5532304-A WEATHERPROOFING ASAHI GLASS COMPANY LTD. (JP) 1996-07-02 US disclosed
EP-0661358-A1 COATING RESIN COMPOSITION ASAHI GLASS COMPANY LTD. (JP) 1995-07-05 EP disclosed