Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674727 | 1.00 | NOS2 (0.50) | NOS2ALDH1A1NOS3TDP1MAPT | |
| SCHEMBL14889018 | 0.84 | FKBP5 (0.43) | NOS2ALDH1A1NOS3TDP1MAPT | |
| SCHEMBL3688848 | 0.80 | MAPT (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL30197316 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL843559 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL18131092 | 0.79 | SMN1; SMN2 (0.50) | NOS2ALDH1A1NOS3TDP1MAPT | |
| SCHEMBL8568773 | 0.78 | MAPT (0.46) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27851817 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29871162 | 0.78 | MEN1 (0.54) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5145767 | 0.78 | MAPT (0.47) | NOS2ALDH1A1NOS3MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952068-A | Synthesis method for Nevirapine intermediates | SHANGHAI SIXIE CHEMICAL TECHNOLOGY CO LTD | 2013-03-06 | — | — | CN | claimed |
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | claimed |
| CN-1284773-C | Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application | BAIRUI GLOBAL CO LTD (VG) | 2006-11-15 | — | — | CN | claimed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | claimed |
| CN-1477099-A | O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same | 百瑞全球有限公司 | 2004-02-25 | — | — | CN | claimed |
| US-3933498-A | Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-01-20 | — | — | US | claimed |
| WO-2025101780-A1 | PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF | OCTANT, INC. (US) | 2025-05-15 | — | — | WO | disclosed |
| US-12297208-B2 | Small molecule inhibitors of KRAS G12C mutant | MERCK SHARP & DOHME LLC (US) | 2025-05-13 | — | — | US | disclosed |
| US-12291538-B2 | Small molecule inhibitors of KRAS G12C mutant | MERCK SHARP & DOHME LLC (US) | 2025-05-06 | — | — | US | disclosed |
| WO-2025052129-A1 | PYRIDINE DERIVATIVES WHICH ACT AS INHIBITORS OF MPTP. | NRG THERAPEUTICS LTD (GB) | 2025-03-13 | — | — | WO | disclosed |
| EP-4090661-B1 | QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR | GRUENENTHAL GMBH (DE) | 2025-03-12 | — | — | EP | disclosed |
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |
| US-20240083913-A1 | Small Molecule Inhibitors of KRAS G12C Mutant | MERCK SHARP & DOHME LLC | 2024-03-14 | — | — | US | disclosed |
| CN-1059723-A | Hete rocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-25 | — | — | CN | disclosed |
| WO-1991011999-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO., INC. (US) | 1991-08-22 | — | — | WO | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0137524-B1 | HAIR DYEING COMPOSITIONS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1988-01-20 | — | — | EP | disclosed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0137524-A1 | Hair dyeing compositions | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | disclosed |
| US-3933498-A | Fogged, direct positive silver halide emulsions containing a bleach inhibiting compound and a Dmin maintainer compound | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297208-B2 | Small molecule inhibitors of KRAS G12C mutant | KRAS, NRAS, HRAS | NOS2 4295/4885ALDH1A1 4287/4885NOS3 3956/4885 |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | NOS2 113/4885ALDH1A1 483/4885NOS3 224/4885 |
| US-20240083913-A1 | Small Molecule Inhibitors of KRAS G12C Mutant | KRAS, NRAS, HRAS | NOS2 4295/4885ALDH1A1 4287/4885NOS3 3956/4885 |
| US-12291538-B2 | Small molecule inhibitors of KRAS G12C mutant | KRAS, NRAS, HRAS | NOS2 4295/4885ALDH1A1 4287/4885NOS3 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.