SCHEMBL28815409

SCHEMBL28815409

O=[N+]([O-])c1cc(Br)ccc1-c1cc[nH]c1-c1ccc(Br)cc1[N+](=O)[O-]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.48
TRPV1 Q8NER1 1/20 0.48
GABRA1 P14867 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 2/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRA6 Q16445 1/20 0.35
GABRG1 Q8N1C3 1/20 0.35
GABRG3 Q99928 1/20 0.35
GABRQ Q9UN88 1/20 0.35
ALDH1A1 P00352 1/20 0.34
ERN1 O75460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204357 0.84 S100A4 (0.61) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL30577700 0.77 NR4A2 (0.47) S100A4TRPV1ALDH1A1MAPTNR4A2
SCHEMBL27814203 0.76 S100A4 (0.47) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL11731287 0.76 GABRA1 (0.54) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL14906924 0.75 S100A4 (0.56) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL5528175 0.75 S100A4 (0.46) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL5321726 0.74 S100A4 (0.54) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL15024965 0.74 IMPDH2 (0.49) S100A4TRPV1CYP2A6PTGES
Hydrogen Sulfide SCHEMBL10764626 0.72 S100A4 (0.49) S100A4TRPV1GABRA1GABRG2GABRB3
SCHEMBL19074303 0.72 TDO2 (0.49) S100A4TRPV1MAPTPKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104341584-A Poly-3, 8-diindolopyrrole as well as preparation method and application thereof UNIV SOUTH CHINA TECH 2015-02-11 CN disclosed