SCHEMBL20439409

CC(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NMT1	P30419	5/20	0.48

▸	NMT2	O60551	4/20	0.48

▸	SIRT6	Q8N6T7	1/20	0.46

▸	SIRT1	Q96EB6	1/20	0.46

▸	TFPI	P10646	1/20	0.44

▸	FURIN	P09958	5/20	0.42

▸	TLR2	O60603	1/20	0.42

▸	SIRT5	Q9NXA8	2/20	0.41

▸	SIRT2	Q8IXJ6	1/20	0.41

▸	PCSK6	P29122	1/20	0.41

▸	IL23R	Q5VWK5	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16189768	0.99	NMT2 (0.46)	NMT1NMT2SIRT6SIRT1TFPI
SCHEMBL20439451	0.98	SIRT6 (0.46)	NMT1NMT2SIRT6SIRT1TFPI
SCHEMBL23879904	0.94	SIRT5 (0.45)	NMT1NMT2SIRT6SIRT1TFPI
SCHEMBL20439405	0.94	SIRT5 (0.43)	NMT1NMT2TFPIFURINSIRT5
SCHEMBL16189773	0.94	SIRT5 (0.43)	NMT1NMT2TFPIFURINSIRT5
SCHEMBL20439410	0.93	TLR2 (0.49)	NMT1NMT2SIRT6SIRT1TFPI
SCHEMBL20439438	0.92	TLR2 (0.48)	NMT1NMT2SIRT6SIRT1TFPI
SCHEMBL16189767	0.92	TLR2 (0.48)	NMT1NMT2SIRT6SIRT1TFPI
SCHEMBL31467781	0.89	SIRT2 (0.48)	NMT1NMT2SIRT6SIRT1FURIN
SCHEMBL20439464	0.87	SIRT5 (0.51)	NMT1NMT2SIRT6SIRT1TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018140563-A1	USE OF APOE MIMETIC PEPTIDES FOR REDUCING THE LIKELIHOOD OF EPILEPTOGENESIS	DUKE UNIVERSITY (US)	2018-08-02	—	—	WO	disclosed