Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | NMT2 | O60551 | 2/20 | 0.48 |
| ▸ | NMT1 | P30419 | 2/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | TFPI | P10646 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.45 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.42 |
| ▸ | NPY4R | P50391 | 5/20 | 0.42 |
| ▸ | NPY1R | P25929 | 4/20 | 0.42 |
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439438 | 0.99 | TLR2 (0.48) | TLR2NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL16189767 | 0.99 | TLR2 (0.48) | TLR2NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL20439464 | 0.94 | SIRT5 (0.51) | TLR2NMT2NMT1SIRT6SIRT1 | |
| Cn-105 SCHEMBL16189774 | 0.94 | SIRT5 (0.47) | TLR2NMT2NMT1TFPISIRT5 | |
| Cn-105 SCHEMBL20439448 | 0.94 | SIRT5 (0.47) | TLR2NMT2NMT1TFPISIRT5 | |
| SCHEMBL20439409 | 0.93 | NMT1 (0.48) | TLR2NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL16189768 | 0.92 | NMT2 (0.46) | TLR2NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL20439451 | 0.91 | SIRT6 (0.46) | TLR2NMT2NMT1SIRT6SIRT1 | |
| SCHEMBL19558265 | 0.87 | FURIN (0.55) | SIRT6SIRT1TFPISIRT5NPY4R | |
| SCHEMBL15896438 | 0.87 | FURIN (0.55) | SIRT6SIRT1TFPISIRT5NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140563-A1 | USE OF APOE MIMETIC PEPTIDES FOR REDUCING THE LIKELIHOOD OF EPILEPTOGENESIS | DUKE UNIVERSITY (US) | 2018-08-02 | — | — | WO | disclosed |